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Agglutination Tests: Types, principle and uses

This post was most recently updated on August 26th, 2019When the specific antibodies (agglutinins) bind to surface antigens of bacteria/virus or any antigens immobilized in particulate matter (such as...

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Counterimmunoelectrophoresis (CIE): Principle, Procedure and Uses

This post was most recently updated on September 27th, 2019 Counterimmunoelectrophoresis (CIE) is a modification of Ouchterlony method that speeds up migration of an antigen and antibody by applying an...

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Interpretation of Hepatitis B Serologic Test Results

This post was most recently updated on August 26th, 2019  Hepatitis B serologic testing involves measurement of several hepatitis B virus (HBV)-specific antigens and antibodies. Different serologic...

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VDRL Test: Principle, procedure, results and interpretation

This post was most recently updated on August 26th, 2019Venereal disease research laboratory (VDRL) test is a nonspecific flocculation test which is used for the screening of syphilis. VDRL test is...

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Anti Streptolysin O (ASO) Test: Principle, Procedure and Interpretation

This post was most recently updated on August 26th, 2019The test principle, procedure and interpretation presented here are based on Latex Anti-Streptolysin O (ASO) test.   It is a rapid latex...

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Rapid Plasma Reagin (RPR) Test: Principle, Procedure and Interpretations

This post was most recently updated on August 26th, 2019The rapid plasma reagin (RPR) test is a macroscopic, nontreponemal  flocculation card test used to screen for syphilis.   Let’s first analyze the...

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Complement Fixation Test: Principle, Procedure and Results

This post was most recently updated on August 26th, 2019The complement fixation test is one of the major traditional tests for the demonstration of presence of specific antigens or antibodies. It...

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Widal test: Principle, Procedure, Results, Interpretation, Significance and...

This post was most recently updated on August 26th, 2019Widal test is a milestone invention in medicine. This test was devised by Frank Widal in 1896. Widal originally described the test to diagnose...

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TPHA: principle, procedure, results and interpretations

This post was most recently updated on August 26th, 2019Treponema pallidum Hemagglutination Assay (TPHA) is a treponemal test for the serologic diagnosis of syphilis, a sexually transmitted infection...

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Coombs Test: Types, Principle, Procedure and Results

This post was most recently updated on August 26th, 2019Coombs test (antiglobulin test) is used to detect the presence of ‘incomplete’ Rh antibodies i.e. IgG antibodies capable of sensitising RBCs but...

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